Coronary heart disease (CHD) is one of the most important leading causes of death in the whole world. Among the different clinical presentations of Coronary heart disease (CHD), acute coronary syndrome (ACS) is the most important and life threatening condition. In spite of their obvious effect, antithrombotic therapies for acute coronary syndrome (ACS) significantly increase bleeding. Hence, it is important to predict the bleeding risk in acute coronary syndrome (ACS) patients in order to modify