The probability of hitting the jackpot is equal for each combination of lottery numbers, but the expected value (in terms of money) does, in fact, depend on the chosen numbers. For example, hitting the UK Lotto jackpot with numbers 1-2-3-4-5-6 would force each winner to share the jackpot with approximately 10 000 other winners. This would mean that 3.8m jackpot would pay about 380£ for each winner. (see http://www.dailymail.co.uk/news/article-2301360/The-Lotto-numbers-avoid-Going-1-2-3-4-5-6-bri